Cytotoxicity and Biocompatibility of Direct and Indirect Pulp Capping Materials
نویسندگان
چکیده
There are several studies about the cytotoxic effects of dental materials in contact with the pulp tissue, such as calcium hydroxide (CH), adhesive systems, resin composite and glass ionomer cements. The aim of this review article was to summarize and discuss the cytotoxicity and biocompatibility of materials used for protection of the dentin-pulp complex, some components of resin composites and adhesive systems when placed in direct or indirect contact with the pulp tissue. A large number of dental materials present cytotoxic effects when applied close or directly to the pulp, and the only material that seems to stimulate early pulp repair and dentin hard tissue barrier formation is CH.
منابع مشابه
In vitro cytotoxicity evaluation of different pulp capping materials: a comparative study.
Direct pulp capping covers the exposed surface of the pulp to maintain its vitality and preserve its functional and biologic activity. The aim of the present study was to compare the biocompatibility effects of seven different pulp-capping materials in vitro: Dycal®, Calcicur®, Calcimol LC®, TheraCal LC®, ProRoot MTA®, MTA-Angelus®, and Biodentine®. Using the Transwell insert methodology by Ala...
متن کاملEvaluation of cytotoxicity and pH changes generated by various dental pulp capping materials - an in vitro study.
INTRODUCTION Various materials are used in direct dental pulp capping method. Their biocompatibility and alkalizing abilities are of primary importance affecting therapeutic effects. The aim of this study was to evaluate and compare the cytotoxicity of various pulp-capping materials on human gingival fibroblasts and investigate the pH changes induced by these materials. MATERIAL AND METHODS H...
متن کاملBiocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials
BACKGROUND In many cases, the indirect pulp treatment (IPT) is an acceptable treatment for deciduous teeth with reversible pulp inflammation. Various medicaments have been used for IPT, ranging from calcium hydroxide and glass ionomers to dentin adhesives. OBJECTIVE This in vitro trial aimed to measure cytotoxicity in a cell culture, comparing the following four adhesives: Xeno® V (XE), Excit...
متن کاملIn Vitro Comparison of Cytotoxicity and Genotoxicity of Three Vital Pulp Capping Materials
Introduction Direct pulp capping (DPC) is a treatment for maintaining pulp vitality and its biological function. Ideally, pulp capping agents are expected to induce pulp cells to form hard tissue. This in vitro study assessed the cytotoxicity and genotoxicity of three vital pulp capping (VPC) agents naming Biodentine (Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (ProRoo...
متن کاملMultifaceted use of ProRoot MTA root canal repair material.
Mineral Trioxide Aggregate (MTA) is a new material recently approved by the FDA for use in pulpal therapy. MTA has been reported to have superior biocompatibility and sealing ability and is less cytotoxic than other materials currently used in pulpal therapy. This report is a review of MTA's physical and biological properties and the clinical techniques of direct pulp capping, apexification, an...
متن کامل